
What it shows
In human blood samples, ozonation caused a dose-dependent increase in microparticles from red and white cells-a measurable immune and oxidative response mechanism, not a clinical endpoint.
Why it matters
Provides biological insight into ozone’s signaling effects on immune modulation and antioxidant balance.
PMC 2022—Ozonation of Whole Blood Results in an Increased Release of Microparticles from Blood Cells

What it shows
A large evidence map reviewed 300+ ozone-therapy studies and reported improvement signals in inflammation, infection control, wound healing, and circulation, with a strong safety profile when applied appropriately.
Why it matters
Adds transparency and context—showing the growing recognition of ozone therapy as a potential adjunct for systemic balance and immune support.
PMC 2023—The Role of Ozone Treatment as Integrative Medicine. An evidence and gap map

What is shows
Preliminary clinical reports describe improved circulation, detoxification, and biochemical markers after EBOO therapy. Research remains early, but findings support continued exploration.
Why it matters
Highlights EBOO’s clinical promise as a regenerative adjunct under expert supervision and strict safety standards.
PMC 200—Extracorporeal blood oxygenation and ozonation: Clinical and biological implications of ozone therapy
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Disclaimer:
Results from EBO2 therapy may vary from person to person. Individual outcomes depend on your unique health condition and response to treatment. EBO2 therapy is not guaranteed to cure or prevent any specific disease. Always discuss your health goals and concerns with your healthcare provider.